Virulence of Shigella flexneri Hybrids Expressing Escherichia coli Somatic Antigens
نویسندگان
چکیده
منابع مشابه
Virulence of Shigella flexneri hybrids expressing Escherichia coli somatic antigens.
The genes controlling either Escherichia coli somatic antigen 8 or 25 were conjugally transferred to virulent Shigella flexneri 2a recipients to determine whether the aquisition of these antigens would affect the virulence of the resulting hybrid. A high proportion of such hybrids were found to be rough and hence were avirulent. Some smooth S. flexneri hybrids which replaced their native group ...
متن کاملVirulence of Escherichia-shigella Genetic Hybrids for the Guinea Pig.
Falkow, Stanley (Walter Reed Army Institute of Research, Washington, D.C.), H. Schneider, L. S. Baron, and S. B. Formal. Virulence of Escherichia-Shigella hybrids for the guinea pig. J. Bacteriol. 86:1251-1258. 1963.-Genetic recombination studies between donor Escherichia coli and recipient Shigella flexneri 2a strains were employed to examine alterations in the virulence of Shigella hybrids fo...
متن کاملRestriction in genetic crosses between Escherichia coli and Shigella flexneri.
Shigella flexneri restricts Escherichia coli deoxyribonucleic acid (DNA) and can modify phage DNA so that it is restricted in E. coli.
متن کاملPhage conversion of Shigella flexneri group antigens.
A temperate phage, designated Sf6, has been isolated from Shigella flexneri 3a. Characterization of Sf6 revealed that it possesses the capacity for converting the S. flexneri 3,4 group antigen complex to group factor 6. Serological studies and chemical analysis of lipopolysaccharide from converted strains suggest that group factor 6 is a reflection of an acetylation of the preexisting 3,4 antig...
متن کاملHuman lactoferrin impairs virulence of Shigella flexneri.
Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virule...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1972
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.6.2.104-111.1972